Pratol

Pratol is a potent inhibitor of NF-κB. Pratol significantly reduces NO and prostaglandin PGE2 production without any cytotoxic in LPS-stimulated RAW 264.7 cells. Pratol reduces proinflammatory cytokines. Pratol can be used in study inflammatory diseases and cancer[1].

Product Specifications

CAS Number

[487-24-1]

Product Name Alternative

7-Hydroxy-4'-methoxyflavone

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pratol.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O)=CC=C13

Molecular Formula

C16H12O4

Molecular Weight

268.26

Precautions

H302, H312, H332

References & Citations

[1]Chung, Y. C. , et al. Anti-inflammatory Effect of Pratol in LPS-stimulated RAW 264.7 Cells via NF-κB Signaling Pathways. Natural Product Communications, 13 (5), 1934578X1801300.