Clavulanic acid
Product Specifications
UNSPSC Description
Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1].
Target Antigen
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clavulanic-acid.html
Purity
99.76
Solubility
DMSO : 13.89 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 7 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O
Molecular Weight
199.162
References & Citations
[1]Parag S Saudagar, et al. Clavulanic acid: a review. Biotechnol Adv. Jul-Aug 2008;26(4):335-51|[2]Neu HC, et al. Clavulanic acid, a novel inhibitor of beta-lactamases. Antimicrob Agents Chemother. 1978 Nov;14(5):650-5.|[3]Beceiro A,et al. In vitro activity and in vivo efficacy of clavulanic acid against Acinetobacter baumannii. Antimicrob Agents Chemother. 2009 Oct;53(10):4298-304.|[4]Soyocak A, et al. Tannic acid exhibits anti-inflammatory effects on formalin-induced paw edema model of inflammation in rats. Hum Exp Toxicol. 2019 Nov;38(11):1296-1301.Eur J Pharmacol. 2024 Sep 28:177017.|Genomics. 2022: 110527.|Int J Mol Sci. 2023 Oct 27, 24(21), 15657.|Biomed Res Int. 2018 Jul 2;2018:3579832. |bioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13(1):1116.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-A0256/Clavulanic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-A0256/Clavulanic-acid-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
58001-44-8
Available Sizes
Curated Selection
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