OZO-H
OZO-H is a GST inhibitor. OZO-H is an OZO derivative with potent anti-cancer effects. OZO-H releases JNK1 from GST-JNK1 complex. OZO-H induces JNK1 phosphorylation and activates c-Jun in cancer cells[1].
Product Specifications
CAS Number
[60027-35-2]
Product Name Alternative
CAY10562
UNSPSC
12352005
Target
Glutathione S-transferase; JNK
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
[O-]C1=C(C2=CC=CC=C2)SN=[O+]1
Molecular Formula
C8H5NO2S
Molecular Weight
179.20
References & Citations
[1]Cui, H., et al., (2008) . 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer chemotherapy and pharmacology, 62 (3), 509–515.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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