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Latent TGF beta 1/TGFB1, Human (Biotinylated, C33S, HEK293, His-Avi)

Latent TGF beta 1/TGFB1 Protein is a large extracellular matrix protein and an associated ligand of fibrillinmicrofibrils. Latent TGF beta 1/TGFB1 Protein, Human (Biotinylated, C33S, HEK293, His-Avi) is a recombinant Biotinylated protein (L30-S390, C33S) produced by HEK293 cells with His-Avi tag[1][2].

Product Specifications

Product Name Alternative

Latent TGF beta 1/TGFB1 Protein, Human (Biotinylated, C33S, HEK293, His-Avi), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/latent-tgf-beta-1-tgfb1-protein-human-biotinylated-hek293-his-avi.html

Purity

95.0

Molecular Formula

7040 (Gene_ID) P01137 (L30-S390, C33S) (Accession)

Molecular Weight

Approximately 40-50 kDa (LAP) kDa & 13-15 kDa (Mature TGF beta 1), based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]J Taipale, et al. Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein. J Cell Biol. 1994 Jan;124 (1-2) :171-81.|[2]C Unsöld, et al. Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains. J Cell Sci. 2001 Jan;114 (Pt 1) :187-197. |[3]Matthias Przyklenk, et al. LTBP1 promotes fibrillin incorporation into the extracellular matrix. bioRxiv. 2022.|[4]Rui Cai, et al. LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation. J Transl Med. 2020 Mar 26;18 (1) :139.|[5]Xiaojun Fu, et al. LTBP1 plays a potential bridge between depressive disorder and glioblastoma. J Transl Med. 2020 Oct 15;18 (1) :391.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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