Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TSG6/TNFAIP6 Antibody Picoband®

Boster Bio Anti-TSG6/TNFAIP6 Antibody Picoband® catalog # A03433-1. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Tumor necrosis factor-inducible gene 6 protein, also known as TSG-6, is a protein that in humans is encoded by the TNFAIP6 gene. The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.

Synonyms

Tumor necrosis factor-inducible gene 6 protein; Hyaluronate-binding protein; TNF-stimulated gene 6 protein; TSG-6; Tumor necrosis factor alpha-induced protein 6; TNF alpha-induced protein 6; TNFAIP6; TSG6

Gene Name

TNFAIP6

Gene ID

7130

UniProt

P98066

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TSG6, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Found in the synovial fluid of patients with rheumatoid arthritis. .

Applications

WB

Field of Research

Cancer, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Immunology, Innate Immunity, Invasion/Microenvironment, Macrophage/Inflammation, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.

References & Citations

1. Entrez Gene: TNFAIP6 tumor necrosis factor, alpha-induced protein 6. 2. Lee TH, Klampfer L, Shows TB, Vilcek J (March 1993) . Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein. J. Biol. Chem. 268 (9) : 6154–60. 3. Milner CM, Day AJ (2004) . TSG-6: a multifunctional protein associated with inflammation.. J. Cell. Sci. 116 (Pt 10) : 1863–73.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

31203 MW

Observed Molecular Weight

31 kDa.

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Tumor necrosis factor-inducible gene 6 protein

Subcellular Location

Late endosome membrane. Peripheral membrane protein. Prevacuolar compartment membrane.

Protein Name

Tumor necrosis factor-inducible gene 6 protein

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human Caspase 3 ELISA Kit
MBS8248335-01 96 Tests

Human Caspase 3 ELISA Kit

Sign In for Pricing
View Details
Human Caspase 3 ELISA Kit
MBS8248335-02 5x 96 Tests

Human Caspase 3 ELISA Kit

Sign In for Pricing
View Details
PBS Blocking buffer with non fat milk
SB0625 1pk, 1L

PBS Blocking buffer with non fat milk

Sign In for Pricing
View Details
ZMAT1 (NM_032441) Human Untagged Clone
SC305450 10 µg

ZMAT1 (NM_032441) Human Untagged Clone

Sign In for Pricing
View Details
Rabbit anti-human Zinc finger protein 285 polyclonal Antibody, HRP conjugated
MBS1498986-01 0.05 mg

Rabbit anti-human Zinc finger protein 285 polyclonal Antibody, HRP conjugated

Sign In for Pricing
View Details
Rabbit anti-human Zinc finger protein 285 polyclonal Antibody, HRP conjugated
MBS1498986-02 0.1 mg

Rabbit anti-human Zinc finger protein 285 polyclonal Antibody, HRP conjugated

Sign In for Pricing
View Details