Pyrroloquinoline quinone (disodium salt)

Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function[1][2].

Product Specifications

CAS Number

[122628-50-6]

Product Name Alternative

PQQ (disodium salt) ; Methoxatin (disodium salt)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Methoxatin-disodium-salt.html

Purity

99.37

Solubility

0.5 M NaOH : 10 mg/mL (ultrasonic) |H2O : 1.25 mg/mL (ultrasonic)

Smiles

O=C(C(N1)=CC(C2=O)=C1C3=C(N=C(C(O[Na])=O)C=C3C(O)=O)C2=O)O[Na]

Molecular Formula

C14H4N2Na2O8

Molecular Weight

374.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Moog RS, et al. Evidence for methoxatin (pyrroloquinolinequinone) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy. Proc Natl Acad Sci U S A. 1986 Nov;83 (22) :8435-9.|[2]Bishop A, et al. Methoxatin (PQQ) in guinea-pig neutrophils. Free Radic Biol Med. 1994 Oct;17 (4) :311-20.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Citation 01

Antioxidants (Basel) . 2024 Jan 15;13 (1) :104.|J Agric Food Chem. 2024 Sep 25;72 (38) :20944-20958.|J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Apr 15:1256:124559.|Antioxidants (Basel) . 2025 Jan 16;14 (1) :102.|Biosens Bioelectron. 2024 Apr 15:250:116049.