PROTAC eDHFR Degrader-1
PROTAC eDHFR Degrader-1 is a PROTAC that is effective degradation of eDHFR-YFP, various POIs-including YFP and Luciferase[1].
Product Specifications
CAS Number
2849442-92-6
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-edhfr-degrader-1.html
Purity
98.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C(CC2=CC(OC)=C(OCCCC(NCCOCCOCCNC3=CC=CC(C(N4C5CCC(NC5=O)=O)=O)=C3C4=O)=O)C(OC)=C2)C=NC(N)=N1
Molecular Formula
C36H44N8O10
Molecular Weight
748.78
References & Citations
[1]Jean M. Etersque, Regulation of eDHFR-tagged proteins with trimethoprim PROTACs.Nat Commun. 2023; 14: 7071.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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