Anti-HLA-E Purified

The antibody MEM-E/08 recognizes an extracellular epitope on native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that antibody is remarkably specific for HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia): HLA-A24, -B7, -B27, -B51, -B54, -C7.

[HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, alpha chain E; major histocompatibility complex, class I, E; MHC class I antigen E]