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VAMP8 Recombinant Antibody, PE Conjugated

Product Specifications

Background

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex.

Synonyms

VAMP8; EDB; Endobrevin; VAMP-8.

Gene ID

8673

Swiss Prot

Q9BV40

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

VAMP8

Clonality

Recombinant

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human VAMP8

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat

Gene ID URL

8673

Isotype

IgG

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