Pantinin-3

Pantinin-3 is an antimicrobial peptide with antitumor activity found in the venom of the emperor scorpion (Pandinus imperator) . Pantinin-3 shows selective toxicity against breast cancer cells (MDA-MB-231) and prostate cancer cells (DU-145) . Pantinin-3 can induce apoptosis in tumor cells. Pantinin-3 can be used in cancer research[1].

Product Specifications

CAS Number

[2383115-06-6]

UNSPSC

12352209

Target

Apoptosis

Type

Peptides

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/pantinin-3.html

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC3=CC=CC=C3)N

Molecular Formula

C72H114N16O18

Molecular Weight

1491.77

References & Citations

[1]Crusca Jr E, et al. Biophysical characterization and antitumor activity of synthetic Pantinin peptides from scorpion's venom[J]. Biochimica et Biophysica Acta (BBA) -Biomembranes, 2018, 1860 (11) : 2155-2165.