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Anti-Aldh1L1 (Staining) Antibody

Our Anti-Aldh1L1 (staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N103/31. It detects rat Aldh1L1 (staining), and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Aldehyde dehydrogenase family 1 member L1 (Aldh1L1) is a member of the aldehyde dehydrogenase family. This protein is an enzyme that catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. It is an astrocyte marker and also is expressed in the liver. It is proposed to play a role in regulation of cellular THF levels and inhibiting cell proliferation. Alterations in Aldh1L1 have been implicated in Congenital Hydrocephalus

Short Description

Our Anti-Aldh1L1 (staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N103/31. It detects rat Aldh1L1 (staining), and is purified by protein a chromatography. It is great for use in IHC, ICC, ELISA.

Synonyms

Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) (FBP-CI)

Gene Name

Aldh1l1 Fthfd

UniProt

P28037

Host

Mouse

Reactivity

Rat

Immunogen

Protein amino acids 1-902 (full-length) of rat Aldh1L1 (accession number P28037) produced recombinantly in E. Coli

Target

Aldh1L1 (staining)

Clonality

Monoclonal

Isotype

IgG1

Clone

N103/31

Type

Primary Antibody

Applications

IHC, ICC, ELISA

Field of Research

Glial and Schwann Cell Markers/Astrocyte Markers

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.91

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:250

WB Dilution

1:2000

Specificity

No cross-reactivity against Aldh1L2

ICC Dilution

1:250

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

Trial Size

1

Conjugate

Unconjugated

IHC Quality Control

1

RRID

AB_10671695

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