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Anti-FGF14/FHF4 Antibody (BSA and Azide free)

Selected Variant

75-096-CF

Size: 100 µL

Our carrier-free Anti-FGF14/FHF4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N56/21. It is KO validated, detects mouse and rat FGF14/FHF4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Fibroblast growth factor 14, FHF4 or FGF14 is encoded by FGF14. FHF4 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.) . FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF14 in found in both the hippocampus and the cerebellum localizes to the axon initial segment. Diseases associated with FGF14 include Spinocerebellar Ataxia and Autosomal Dominant Cerebellar Ataxia.

Short Description

Our Anti-FGF14/FHF4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N56/21. It is KO validated, detects human, mouse, non-human primate, and rat FGF14/FHF4, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Fibroblast growth factor (FGF)

Gene Name

Fgf14

UniProt

O89096

Host

Mouse

Reactivity

Human, Mouse, Non-Human Primate, and Rat

Immunogen

Fusion protein amino acids 1-252 (full-length) of mouse FGF14b (accession number O89096) produced recombinantly in E. Coli

Target

FGF14/FHF4

Clonality

Monoclonal

Isotype

IgG1

Clone

N56/21

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Axonal Markers/Neurogenesis and Development

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS

Molecular Weight

28 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Specificity

Cross-reacts with FGF14a and FGF14b Does not cross-react with FGF11, FGF12 or FGF13

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

Conjugate

Unconjugated

IHC Quality Control

1

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