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Anti-Pancreatic Polypeptide Antibody

Our mouse Pancreatic Polypeptide monoclonal antibody from Antibodies Incorporated is produced in-house from clone 6. It detects human Pancreatic Polypeptide and is Protein A or Protein G purified. Works in ELISA, WB.

Product Specifications

Background

Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.

Synonyms

PPY, PH, PNP, PP, pancreatic polypeptide prohormone, pancreatic polypeptide Y, pancreatic prohormone, prepro-PP (prepropancreatic polypeptide)

Gene Name

PPY

NCBI Gene ID

5539

UniProt

P01298

Host

Mouse

Reactivity

Human

Immunogen

Synthetic human PP

Target

Pancreatic Polypeptide

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

6

Type

Primary Antibodies

Applications

ELISA, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

10 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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