Anticancer agent 73
Product Specifications
UNSPSC Description
Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo[1].
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-73.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)OC(C2=CC=C(OC)C=C2)=N1)OCC
Molecular Weight
261.27
References & Citations
[1]Peng T, et al. Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis. J Med Chem. 2022 Jun 13.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147918/Anticancer-agent-73-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147918/Anticancer-agent-73-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
9007-83-4
Available Sizes
Curated Selection
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