Apyramide
Apyramide is an anti-inflammatory agent (NSAID) and behaves as a proagent of indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.
Product Specifications
CAS Number
68483-33-0
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Apyramide.html
Purity
99.06
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C(NC(C)=O)C=C1)CC2=C(C)N(C(C3=CC=C(Cl)C=C3)=O)C4=C2C=C(OC)C=C4
Molecular Formula
C27H23ClN2O5
Molecular Weight
490.93
References & Citations
[1]Sauvaire D, et al. Pharmacological activity and toxicity of apyramide: comparison with non-steroidal anti-inflammatory agents. Drugs Exp Clin Res. 1987;13 (5) :247-52.|[2]M Cociglio, et al. Pharmacokinetics of an indomethacin pro-drug: apyramide after intravenous administration in dog. Eur J Drug Metab Pharmacokinet. Oct-Dec 1991;16 (4) :275-80.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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