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Recombinant IGF2R/CI-M6PR Monoclonal Antibody

Product Specifications

Background

The HAP1 is a nuclear enzyme that apparently performs two distinct roles in the cellular defense against oxidative stress. One well-established role is in the repair of a variety of lesions induced in DNA either by spontaneous hydrolysis or by reactive oxygen species (ROS) . This function has been characterized in great detail and the roles played by individual active site amino acid residues have been defined. The second role, which was identified only relatively recently and is still not characterized in detail, is to regulate the DNA binding activity of a group of nuclear factors.

Abbreviation

IGF2R/CI-M6PR

UniProt

P11717

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human IGF2R/CI-M6PR fragment

Target

MPR; IGF2R; CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR 300; MPR1; MPR300; MPRI; cation-independent mannose-6-phosphate receptor; IGF-IIR;300 kDa mannose 6 phosphate receptor;300 kDa mannose 6-phosphate receptor; cation independent; Cation independent mannose 6 phosphate receptor; CD222 antigen; CI Man 6 P receptor; CI Man-6-P receptor; CI MPR; CI-MPR; IGF 2 receptor; IGF 2R; IGF II receptor; IGF2 receptor; IGF-II receptor; Insulin like growth factor 2 receptor; Insulin like growth factor II receptor; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; M6P R; M6P/IGF2 receptor; M6PR; mannose 6 phosphate receptor

Clonality

Monoclonal,Recombinant

Clone

A571

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology; Tags & Cell Markers; Signal Transduction

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:200

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

274 kDa

Observed Molecular Weight

300 kDa

Isotype

IgG, κ

Available Sizes

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