Recombinant IGF2R/CI-M6PR Monoclonal Antibody
Product Specifications
Background
The HAP1 is a nuclear enzyme that apparently performs two distinct roles in the cellular defense against oxidative stress. One well-established role is in the repair of a variety of lesions induced in DNA either by spontaneous hydrolysis or by reactive oxygen species (ROS) . This function has been characterized in great detail and the roles played by individual active site amino acid residues have been defined. The second role, which was identified only relatively recently and is still not characterized in detail, is to regulate the DNA binding activity of a group of nuclear factors.
Abbreviation
IGF2R/CI-M6PR
UniProt
P11717
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human IGF2R/CI-M6PR fragment
Target
MPR; IGF2R; CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR 300; MPR1; MPR300; MPRI; cation-independent mannose-6-phosphate receptor; IGF-IIR;300 kDa mannose 6 phosphate receptor;300 kDa mannose 6-phosphate receptor; cation independent; Cation independent mannose 6 phosphate receptor; CD222 antigen; CI Man 6 P receptor; CI Man-6-P receptor; CI MPR; CI-MPR; IGF 2 receptor; IGF 2R; IGF II receptor; IGF2 receptor; IGF-II receptor; Insulin like growth factor 2 receptor; Insulin like growth factor II receptor; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; M6P R; M6P/IGF2 receptor; M6PR; mannose 6 phosphate receptor
Clonality
Monoclonal,Recombinant
Clone
A571
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology; Tags & Cell Markers; Signal Transduction
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:200
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/CBO1O3ow
Calculated Molecular Weight
274 kDa
Observed Molecular Weight
300 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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