8-OAc

8-OAc is a potent and selective mitochondrial electron transport chain (ETC) complex I inhibitor. 8-OAc exhibits cytotoxicity against cancer cell lines[1].

Product Specifications

CAS Number

[2550395-87-2]

UNSPSC

12352005

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-oac.html

Smiles

O=C(NCCC(/C=C\C[C@H](OC(C)=O)C(C)(C)C1=NC(C/C=C\CC=C)=CS1)=C)OC

Molecular Formula

C24H34N2O4S

Molecular Weight

446.60

References & Citations

[1]Naibedya Dutta, et al. Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging. Geroscience. 2024 Apr 3.