4-O-Methyl-ascochlorin
4-O-Methyl-ascochlorin (Compound MAC) is a derivative of Ascochlorin that selectively induces apoptosis and G1 phase arrest in K562 leukemia cells while downregulating c-Myc expression. It enhances the phosphorylation of AMPK and inhibits the phosphorylation of mTOR and its target proteins [including p70S6 K and 4E-BP-1]. 4-O-Methyl-ascochlorin is useful for leukemia research.
Product Specifications
CAS Number
38561-40-9
Smiles
C (/C=C (/C=C/[C@]1 (C) [C@@H] (C) C (=O) CC[C@H]1C) \C) C2=C (OC) C (Cl) =C (C) C (C=O) =C2O
Molecular Formula
C24H31ClO4
Molecular Weight
418.96
Notes
For research use only.
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