Met-AMS (TEA)
Product Specifications
UNSPSC Description
Met-AMS TEA (compound 50), a sulfamate analogue of methionyl adenylate, is a potent Escherichia coli methionyl-tRNA synthetase (MetRS) inhibitor (IC50 of 7 nM)[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/met-ams-tea.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1COS(=O)(NC([C@H](CCSC)N)=O)=O.CCN(CC)CC
Molecular Weight
578.71
References & Citations
[1]Jeewoo Lee, et al. N-Alkoxysulfamide, N-hydroxysulfamide, and sulfamate analogues of methionyl and isoleucyl adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1087-92.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159627A/Met-AMS-TEA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159627A/
Clinical Information
No Development Reported
CAS Number
1122489-97-7
Available Sizes
Curated Selection
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