Azo-PROTAC-4C-cis
Azo-PROTAC-4C-cis is a BCR-ABL PROTAC degrader, exhibiting a lower efficiency in degrading BCR-ABL compared to its trans isomer, Azo-PROTAC-4C-trans. The cis isomer forms as a result of a configurational change of Azo-PROTAC-4C-trans when exposed to ultraviolet light (UV) . Under visible light, Azo-PROTAC-4C-cis can be converted back to the highly active Azo-PROTAC-4C-trans, initiating protein degradation. This compound is useful for studying myeloid leukemia.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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