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Pomalidomide-5-C7-NH2

Pomalidomide-5-C7-NH2 is an E3 ligase ligand-linker conjugate that incorporates the 5-Aminothalidomide based CRBN ligand (HY-103596) and linker. Pomalidomide-5-C7-NH2 can be used for synthesis of PROTAC BT-O2C (HY-174866).

Product Specifications

CAS Number

2412056-40-5

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

NCCCCCCCNC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1

Molecular Formula

C20H26N4O4

Molecular Weight

386.44

References & Citations

[1]Marsh GP, et al. Development of p300-targeting degraders with enhanced selectivity and onset of degradation. RSC Med Chem. 2025 Mar 3;16 (5) :2049-2060.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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