PROTAC BRD4 Degrader-41
PROTACBRD4 Degrader-41 (Compound A5) is a BRD4 PROTAC degrader with a DC50 of 0.97 nM. It exhibits potent antiproliferative activity against various cancer cells, including AML, lymphoma, breast cancer, ovarian cancer, and non-small cell lung cancer. The compound induces G0/G1 phase arrest and apoptosis in MV4-11 cells and downregulates c-Myc transcription levels.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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