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Feniralstat hydrochloride

Feniralstat (compound 30) hydrochloride is a pyrazole derivative and an effective inhibitor of kallikrein, exhibiting an IC50 of 6.7 nM against human plasma kallikrein (pKal) . It shows no inhibitory effects on human KLK1, FXIa, or factor XIIa, with IC50 values exceeding 40 μM for each.

Product Specifications

CAS Number

2340299-00-3

Smiles

Cl.O=C1C=CC (F) =CN1CC2=CC=C (C=C2) CN3N=C (C (=C3) C (=O) NCC4=NC=CC (OC) =C4F) COC

Molecular Formula

C26H26ClF2N5O4

Molecular Weight

545.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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