Question 1

What is the catalog number for CGAS-IN-8?

Accepted Answer

The catalog number for CGAS-IN-8 is orb3174334.

Question 2

What sizes are available for CGAS-IN-8?

Accepted Answer

CGAS-IN-8 is available in the following size(s): 50 mg, 10 mg.

Question 3

How many pack sizes does CGAS-IN-8 come in?

Accepted Answer

CGAS-IN-8 is available in 2 different pack sizes.

Question 4

Is CGAS-IN-8 in stock?

Accepted Answer

CGAS-IN-8 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 5

What is CGAS-IN-8 used for?

Accepted Answer

CGAS-IN-8 is an indazole-based inhibitor of cyclic GMP-AMP synthase (cGAS), demonstrating an IC50 of 6 nM for human cGAS. It inhibits the production of cGAMP in THP-1 cells with an IC50 of 0.12 μM. Notably, cGAS-IN-8 does not inhibit hERG activity and is applicable in the study of autoimmune disease

Question 6

What is the recommended dilution for this antibody?

Accepted Answer

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

Question 7

What is the recommended storage temperature after reconstitution?

Accepted Answer

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Question 8

Can this product be used in multiplex assays?

Accepted Answer

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

CGAS-IN-8

Product Specifications

Storage Conditions

Notes

Available Sizes

Frequently Asked Questions

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