Recombinant C5 Monoclonal Antibody
Product Specifications
Background
C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa) . C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha chain) .
Abbreviation
C5
UniProt
P01031
Host
Rabbit
Reactivity
Human
Immunogen
Peptide. This information is proprietary to PTMab.
Target
Complement C; CPAMD; C5a; C5a anaphylatoxin; C5Da; Complement C5; ECLZB; C5; CPAMD4
Clonality
Monoclonal,Recombinant
Clone
A734
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology; Signal Transduction; Cell Biology; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:1000-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
188 kDa
Observed Molecular Weight
125 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2132302 1.0 µg DNA
SFRS2B sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 
GTR15279176 1 Vial
Lentiviral mouse Lyg2 shRNA (UAS) - Lentiviral mouseLyg2 shRNA (UAS, GFP) (25)
Sign In for Pricing
View Details