Janagliflozin
Janagliflozin is an orally active and highly selective inhibitor of sodium-glucose co-transporter protein 2 (SGLT2) with an IC50 value of 0.0058 μM, and an IC50 of 4.802 μM for SGLT1. It inhibits SGLT2 in the proximal renal tubules, reducing glucose reabsorption and promoting urinary glucose excretion (UGE), thereby lowering blood glucose levels. Janagliflozin holds potential for research in treating type 2 diabetes.
Product Specifications
CAS Number
1800115-22-3
Smiles
O ([C@@H]1C[C@@]2 ([C@@] (C2) (C1) [H]) [H]) C3=CC=C (CC4=CC (=CC=C4Cl) [C@@H]5O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]5O) C=C3
Molecular Formula
C25H29ClO6
Molecular Weight
460.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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