Recombinant S. cerevisiae TIM16 Protein
Product Specifications
Background
Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM16 is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. TIM16 may act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
Abbreviation
TIM16
Synonyms
Mitochondrial import inner membrane translocase subunit TIM16; PAM16; Presequence translocated-associated motor subunit PAM16; TIM16
UniProt
P42949
Accession Number
P42949
Expression System
E.coli
Tag
None
Sequence
Thr54-Ala119
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
7.9 kDa
Observed Molecular Weight
11 kDa
Species
S. cerevisiae
Available Sizes
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