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IIIM-1266

IIIM-1266 is an inhibitor of the NLRP3 inflammasome. It suppresses the release of IL-1β in murine macrophages (J774A.1 cells) with an IC50 of 2.3 μM and significantly reduces the protein expression levels of mature IL-1β. IIIM-1266 is applicable for inflammation research.

Product Specifications

CAS Number

2468202-93-7

Smiles

O=C1NC2C=CC (=C3C=CC=C1C32) S (=O) (=O) N (CC) CC

Molecular Formula

C15H18N2O3S

Molecular Weight

306.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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