Recombinant FBXW7 Monoclonal Antibody

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination.

FBX; CDC; FBXO; hCdc; FBW; SEL; FBXW7; AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; SEL-10; SEL10; hAgo; hCdc4; Archipelago; Archipelago homolog; DKFZp686F23254; Drosophila; Drosophila) ; E3 ubiquitin protein ligase; F box and WD 40 domain protein 7; F box and WD 40 domain protein 7 (archipelago homolog; F box and WD repeat domain containing 7; F box protein FBW7; F box protein FBX30; F box protein SEL 10; F box protein SEL10; F-box and WD repeat domain containing 7; F-box and WD-40 domain-containing protein 7; F-box protein FBX30; F-box/WD repeat-containing protein 7; FLJ16457; homolog of; Homolog of C elegans sel 10; Homolog of C.elegans sel10; S.cerevisiae; SEL 10