Recombinant FBXW7 Monoclonal Antibody
Product Specifications
Background
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination.
Abbreviation
FBXW7
UniProt
Q969H0
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human FBXW7 fragment
Target
FBX; CDC; FBXO; hCdc; FBW; SEL; FBXW7; AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; SEL-10; SEL10; hAgo; hCdc4; Archipelago; Archipelago homolog; DKFZp686F23254; Drosophila; Drosophila) ; E3 ubiquitin protein ligase; F box and WD 40 domain protein 7; F box and WD 40 domain protein 7 (archipelago homolog; F box and WD repeat domain containing 7; F box protein FBW7; F box protein FBX30; F box protein SEL 10; F box protein SEL10; F-box and WD repeat domain containing 7; F-box and WD-40 domain-containing protein 7; F-box protein FBX30; F-box/WD repeat-containing protein 7; FLJ16457; homolog of; Homolog of C elegans sel 10; Homolog of C.elegans sel10; S.cerevisiae; SEL 10
Clonality
Monoclonal,Recombinant
Clone
A220
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cell Biology; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:100-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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