HsClpP activator-2
HsClpP activator-2 is an orally active HsClpP agonist with a KD of 40 nM. It exhibits significant inhibitory effects on small cell lung cancer (SCLC) cells, including H69 (IC50 = 0.17 μM) and H82 (IC50 = 0.19 μM) . This compound disrupts mitochondrial membrane potential (MMP), induces apoptosis (apoptosis), and promotes ROS production in H82 cells. Additionally, HsClpP activator-2 significantly suppresses tumor growth in non-SMC cell xenograft models and is applicable for research in small cell lung cancer (SCLC) .
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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