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3'2'-cGAMP

3'2'-cGAMP (c[A (2',5') pG (3',5') p]) is an isomer of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) . It selectively activates fruit fly STING (dSTING), initiating the dSTING-NF-κB signaling pathway, driving the expression of Sting-regulated genes, and conferring a potent antiviral state in vivo. Additionally, 3'2'-cGAMP resists cleavage by viral poxin and is useful in viral infection research.

Product Specifications

CAS Number

1615704-64-7

Smiles

O[C@H]1[C@@]2 ([C@@H] (OC1 (COP (=O) (O) O[C@@]3 ([C@@] (COP (=O) (O) O2) (O[C@H] ([C@@H]3O) N4C5=C (N=C4) C (=O) N=C (N) N5) [H]) [H]) [H]) N6C=7C (N=C6) =C (N) N=CN7) [H]

Molecular Formula

C20H24N10O13P2

Molecular Weight

674.42

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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