Letrozole
Product Specifications
CAS Number
112809-51-5
Synonyms
CGS 20267
Target
Aromatase
Applications
Endocrinology & Hormones
Smiles
C1=CC (=CC=C1C#N) C (C2=CC=C (C=C2) C#N) N3C=NC=N3
Molecular Formula
C17H11N5
Additionnal Information
Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.
Storage Conditions
2 years -80 in solvent
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