DBCO-PEG3-Glu-Val-Cit-PABC-MMAE
Product Specifications
UNSPSC Description
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG3-Glu-Val-Cit-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162) and can be used for synthesis of dual-drug ADC[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-peg3-glu-val-cit-pabc-mmae.html
Smiles
O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC(COCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1729.06
References & Citations
[1]Yamazaki CM, et al. Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance. Nat Commun. 2021 Jun 10;12(1):3528.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164309/DBCO-PEG3-Glu-Val-Cit-PABC-MMAE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164309/
Clinical Information
No Development Reported
CAS Number
2861998-23-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2613220-01 48 Well
Guinea pig leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (LILRA5) ELISA Kit
Ask
View Details 
MBS2613220-02 96 Well
Guinea pig leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (LILRA5) ELISA Kit
Ask
View Details MBS2613220-03 5x 96 Well
Guinea pig leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (LILRA5) ELISA Kit
Ask
View Details 
MBS2613220-04 10x 96 Well
Guinea pig leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (LILRA5) ELISA Kit
Ask
View Details 