Pyrimidine-5-boronic acid pinacol ester

Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. At the same time, it should be noted that it may be a genotoxic impurity (GTIs) [1].

Product Specifications

CAS Number

[321724-19-0]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pyrimidine-5-boronic-acid-pinacol-ester.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1(C)OB(C2=CN=CN=C2)OC1(C)C

Molecular Formula

C10H15BN2O2

Molecular Weight

206.05

Precautions

H302, H315, H319, H335

References & Citations

[1]Hansen M M, et al. Boronic Acids and Derivatives Probing the Structure-Activity Relationships for Mutagenicity[J]. Organic Process Research & Development, 2015, 19 (11) : 1507-1516.