Ligritinib
Ligritinib (AB801) is an orally active inhibitor of the AXL receptor tyrosine kinase. By inhibiting the kinase activity of AXL, Ligritinib blocks its downstream signaling pathways. It is utilized in cancer research, particularly in studies involving non-small cell lung cancer (NSCLC) in combination with chemotherapy.
Product Specifications
CAS Number
3024588-48-2
Field of Research
Signal Transduction
Smiles
CC1=C (C2=CC=C (C=3C4=CC (C=5C=C6CC[C@@H] (N7C8CC7COC8) CCC6=CC5) =CN=C4NN3) N=C2) N=CC=C1
Molecular Formula
C33H32N6O
Molecular Weight
528.65
Storage Conditions
-20°C
Notes
For research use only.
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