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PF-03814735

PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.

Product Specifications

CAS Number

942487-16-3

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Smiles

CC (=O) NCC (=O) N1[C@H]2CC[C@@H]1c1cc (Nc3ncc (c (NC4CCC4) n3) C (F) (F) F) ccc21

Molecular Formula

C23H25F3N6O2

Molecular Weight

474.48

Storage Conditions

-20°C

Notes

For research use only.

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