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Warfarin

Warfarin (Coumafene) is a vitamin K antagonist, and it works by blocking the action of vitamin K, which is necessary for the synthesis of clotting factors in the liver. Warfarin blocks the action of vitamin K by inhibiting the enzyme gamma-glutamyl carboxylase, which is responsible for the carboxylation of glutamate residues in the clotting factors. This prevents the production of functional clotting factors, leading to an anticoagulant effect.

Product Specifications

CAS Number

81-81-2

Product Name Alternative

Coumadin, Coumafene, Athrombine-K, Prothromadin, WARF 42, WARF42, WARF-42, Warfarin, vitamin K

Field of Research

Pharmacology & Drug Discovery

Purity

99.01% (May vary between batches)

Solubility

DMSO:40 mg/mL (129.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.49 mM)

Smiles

CC (=O) CC (c1ccccc1) c1c (O) c2ccccc2oc1=O

Molecular Formula

C19H16O4

Molecular Weight

308.3279

Storage Conditions

-20°C

Notes

For research use only.

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