Z1609609733
Z1609609733 (Compound 18) is a non-covalent inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 1.46 μM. It effectively suppresses serine synthesis, interferes with cancer metabolism, and completely halts cell proliferation.
Product Specifications
CAS Number
2375374-15-3
Field of Research
Metabolism Research
Smiles
O=C (OC (OC (=O) C (C=1C=NC=CC1) C2=CC=C (C=C2) C3 (NC (=O) C4=CC=5C (Cl) =C (Cl) C=CC5N4C) COC3) C) C
Molecular Formula
C30H27Cl2N3O6
Molecular Weight
596.46
Storage Conditions
-20°C
Notes
For research use only.
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