IKZF2-degrader 1
IKZF2-degrader 1 (Compound 31) is a molecular glue-type degrader of IKZF2 with a DC50 of 0.5 nM. It exhibits relatively low degradation activity against CK1α, with a DC50 of 210 nM. This compound is applicable in research focused on IKZF2-dependent cancers.
Product Specifications
CAS Number
2983840-43-1
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C4=NC=5C (=NNC5C (=C4) CN6CCCC6) NC (C) C) C (F) =C3C2) CC1
Molecular Formula
C27H30FN7O3
Molecular Weight
519.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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