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TEAD1/3/4-IN-1

TEAD1/3/4-IN-1 (compound 1) is an inhibitor of TEAD1/3/4 that suppresses YAP/TAZ-TEAD interactions. It exhibits antitumour activity against NF2-deficient NCI-H226 cells and may be employed in studies of cancer and diseases mediated by Hippo pathway abnormalities.

Product Specifications

CAS Number

2762619-63-4

Product Name Alternative

TEAD1/3/4IN1

Field of Research

Stem Cell & Developmental Biology

Purity

99.25% (May vary between batches)

Solubility

DMSO:20 mg/mL (49.1 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (4.91 mM)

Smiles

O=C (C (F) =C) N1CC (N2C (=O) N (C3=CC=C (C=C3) C (F) (F) F) C4=NC=CN=C42) C1

Molecular Formula

C18H13F4N5O2

Molecular Weight

407.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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