TAMRA-isoADPr
Product Specifications
UNSPSC Description
TAMRA-isoADPr is a fluorescently tagged iso-ADP-ribose tracer compound. TAMRA-isoADPr is a high-affinity tracer for the RNF146 WWE domain with a Kd of 45.2 nM[1].
Target Antigen
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tamra-isoadpr.html
Solubility
10 mM in DMSO
Smiles
CN(C)C1=CC(OC(C=C(N(C)C)C=C2)=C2C34OC(C5=CC(C(NCCCCCCNC(CCC6=CN([C@H]7[C@@H](O[C@@H]8[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O8)[C@H](N9C=NC%10=C9N=CN=C%10N)O[C@@H]7COP(O)(O)=O)N=N6)=O)=O)=CC=C54)=O)=C3C=C1
Molecular Weight
1193.06
References & Citations
[1]Kewen Peng, et al. Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS Chem Biol. 2024 Jan 18.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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