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TAMRA-isoADPr

Product Specifications

UNSPSC Description

TAMRA-isoADPr is a fluorescently tagged iso-ADP-ribose tracer compound. TAMRA-isoADPr is a high-affinity tracer for the RNF146 WWE domain with a Kd of 45.2 nM[1].

Target Antigen

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tamra-isoadpr.html

Solubility

10 mM in DMSO

Smiles

CN(C)C1=CC(OC(C=C(N(C)C)C=C2)=C2C34OC(C5=CC(C(NCCCCCCNC(CCC6=CN([C@H]7[C@@H](O[C@@H]8[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O8)[C@H](N9C=NC%10=C9N=CN=C%10N)O[C@@H]7COP(O)(O)=O)N=N6)=O)=O)=CC=C54)=O)=C3C=C1

Molecular Weight

1193.06

References & Citations

[1]Kewen Peng, et al. Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS Chem Biol. 2024 Jan 18.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-162175/TAMRA-isoADPr-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-162175/

Clinical Information

No Development Reported

Curated Selection

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