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EGFR-IN-160

EGFR-IN-160 is an EGFR inhibitor with IC50 values of 1.62, 0.49, and 0.98 μM for EGFRWT, EGFRT790M, and EGFRL858R/T790M/C797S, respectively. It can induce cell cycle arrest at the G2/M and S phases and apoptosis (Apoptosis) in NCI-H522 cells, demonstrating anticancer properties. Additionally, EGFR-IN-160 exhibits antioxidant activity against DPPH (IC50: 12.11 μM) and H2O2 (IC50: 8.89 μM) .

Product Specifications

CAS Number

2172879-84-2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

O=C1N=C (C=C (N1) C=2C=CC (O) =C (OC) C2) C=3OC=CC3

Molecular Formula

C15H12N2O4

Molecular Weight

284.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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