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3-AP-Me

3-AP-Me, a dimethylated derivative of the ribonucleotide reductase inhibitor 3-AP, induces apoptosis by activating ER stress through eIF2α phosphorylation and upregulating ATF4/ATF6. It also activates JNK/p38 kinases and XBP1 splicing. This compound is used in cancer research for studying stress pathways in vitro and in vivo.

Product Specifications

CAS Number

1184391-57-8

Field of Research

Cell Biology, Signal Transduction

Smiles

S=C (NN=CC1=NC=CC=C1N) N (C) C

Molecular Formula

C9H13N5S

Molecular Weight

223.298

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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