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DGAT2L4 Antibody - C-terminal region : HRP (ARP44425_P050-HRP)

Product Specifications

Gene Name

Acyl-CoA wax alcohol acyltransferase 2

Gene Aliases

WS, DC4, ARAT, MFAT, DGAT2L4

Gene ID

158835

Swiss Prot

Q6E213

Accession Number

NP_001002254

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human DGAT2L4

Target

DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Yen, C.L., (2005) J. Lipid Res. 46 (11), 2388-2397

Shipping Conditions

Wet Ice

Product Datasheet

Anti-AWAT2 (ARP44425_P050-HRP) antibody

Protein Length

333

NCBI Gene Symbol

AWAT2

NCBI GB Accession Number

AWAT2

Host or Source

Rabbit

Protein Name

Acyl-CoA wax alcohol acyltransferase 2

Nucleotide Accession Number

NM_001002254

Peptide Sequence

GEPLPMPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII

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