SPA0355
SPA0355 is a thiourea-based small molecule that inhibits osteoclast formation and promotes osteoblast differentiation. It suppresses RANKL-induced MAPK, Akt, and NF-κB pathways in vitro and protects against bone loss in ovariectomized mouse models, making it a valuable research tool for studying bone metabolism and osteoporosis.
Product Specifications
CAS Number
1251839-15-2
Field of Research
Signal Transduction
Smiles
S=C (NC1=CC=C (OCCN2C=3C=CC=CC3OC=4C=CC=CC42) C=C1) NC
Molecular Formula
C22H21N3O2S
Molecular Weight
391.486
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4900602 1.0 µg DNA
Tmem209 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
