GJG057
GJG057 is a potent and selective oral inhibitor of Leukotriene C4 synthase (LTC4S), demonstrating an IC50 of 44 nM in human whole blood. It shows anti-inflammatory efficacy in murine asthma models, supporting its research use in studying allergic inflammation pathways in both in vitro and in vivo settings.
Product Specifications
CAS Number
2761767-18-2
Product Name Alternative
GJG-057
Field of Research
Metabolism Research
Purity
99.80% (May vary between batches)
Solubility
DMSO:40 mg/mL (87.64 mM)
Smiles
O=C1N (C2=CC=C (F) C (F) =C2) C3 (CCN (C=4N=CN=C (OCC (F) (F) F) C4) CC3) CCC1
Molecular Formula
C21H21F5N4O2
Molecular Weight
456.41
Storage Conditions
-20°C
Notes
For research use only.
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