Pks13-IN-2

Pks13-IN-2 (Compound 43) is an orally bioavailable inhibitor targeting the essential mycobacterial Pks13 enzyme, demonstrating potent in vitro activity against M. tuberculosis H37Rv (MIC 0.8-1.8 μM) . Its favorable metabolic stability in hepatic models supports its utility for both in vitro and in vivo tuberculosis drug discovery research.