KRAS G12D inhibitor 26
Compound 64B is a potent and selective KRAS G12D inhibitor with an IC50 of ≤100 nM. It is a valuable research tool for investigating KRAS-driven oncogenesis in both cellular assays and in vivo models, supporting the development of targeted cancer therapies.
Product Specifications
CAS Number
2972625-49-1
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.93% (May vary between batches)
Solubility
DMSO:80 mg/mL (120.62 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (4.98 mM)
Smiles
CN1[C@]2 (C=3C (CCC2) =CC=CC3) CC=4C (C1) =C (N=C (OC[C@@]56N (C[C@H] (F) C5) CCC6) N4) N7CC=8N (CCC7) N=C (C (N (C) C) =O) C8Cl
Molecular Formula
C35H44ClFN8O2
Molecular Weight
663.23
Storage Conditions
-20°C
Notes
For research use only.
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