PDE1B Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
NCBI Gene ID
5153
Swiss Prot
Q01064
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
NCI-H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 59kDa
Fragment
IgG
Symbol
PDE1B
Positive Control 2
THP-1
Positive Control 3
Mouse brain
Positive Control 4
Mouse spleen
Positive Control 5
Mouse spinal cord
NCBI Official Name
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
NCBI Organism
Homo sapiens
Other Product Names
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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