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PDE1B Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

NCBI Gene ID

5153

Swiss Prot

Q01064

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

NCI-H460

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=18-502

Calculated Molecular Weight

Observed: 59kDa

Fragment

IgG

Symbol

PDE1B

Positive Control 2

THP-1

Positive Control 3

Mouse brain

Positive Control 4

Mouse spleen

Positive Control 5

Mouse spinal cord

NCBI Official Name

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

NCBI Organism

Homo sapiens

Other Product Names

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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