Oxatomide
Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM) . Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.
Product Specifications
CAS Number
60607-34-3
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (586.10 mM; Ultrasonic)
Smiles
O=C1NC2=C (C=CC=C2) N1CCCN1CCN (CC1) C (C1=CC=CC=C1) C1=CC=CC=C1
Molecular Formula
C27H30N4O
Molecular Weight
426.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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